First report of a clinical isolate of Candida haemulonii in Brazil
نویسندگان
چکیده
João Nobrega de Almeida Jr., Adriana Lopes Motta, Flávia Rossi, Edson Abdala, Ligia Camera Pierrotti, Adriana Satie Gonçalves Kono, Maria Del Pilar Estevez Diz, Gil Benard, Gilda Maria Barbaro Del Negro I Hospital das Clı́nicas da Faculdade de Medicina da Universidade de São Paulo, Microbiology Section, Divisão de Laboratório Central, São Paulo/SP, Brazil. II Instituto do Câncer, Faculdade de Medicina da Universidade de São Paulo, São Paulo/SP, Brazil. III Hospital das Clı́nicas da Faculdade de Medicina da Universidade de São Paulo e Instituto de Medicina Tropical da Universidade de São Paulo, Laboratory of Medical Mycology (LIM-53) – Clinical Dermatologic Division, São Paulo/SP, Brazil.
منابع مشابه
Candida haemulonii complex: species identification and antifungal susceptibility profiles of clinical isolates from Brazil.
OBJECTIVES The emerging fungal pathogens comprising the Candida haemulonii complex (Candida haemulonii, Candida haemulonii var. vulnera and Candida duobushaemulonii) are notable for their antifungal resistance. Twelve isolates with phenotypic similarity to C. haemulonii were recovered from patients in Brazilian hospitals. Here we aimed to identify these isolates by a molecular approach, using t...
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The first outbreak of Candida haemulonii fungemia is described. The seven isolates from the blood of four neonates were identified by DNA sequencing of the ribosomal DNA. They were all resistant to amphotericin B, fluconazole, and itraconazole. This report highlights the emergence of C. haemulonii as an opportunistic pathogen in immunocompromised patients.
متن کاملTransient fungemia caused by an amphotericin B-resistant isolate of Candida haemulonii.
A bloodstream infection due to Candida haemulonii afflicting a patient with fever and a medical history of megaloblastic anemia is reported. The clinical isolate was misidentified by the API 20C and VITEK identification systems. The results of susceptibility tests showed that the MIC of amphotericin B for C. haemulonii was 4 microg/ml. Additional susceptibility testing procedures based on the u...
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infection have been reported in immunosuppressed persons, both in HIV/AIDS patients (manifesting as pulmonary infection in 1 patient and disseminated disease in the other) (6). In our study, the im-munocompromised patient with M. arupense tenosynovitis received canakinumab, a relatively new biologic agent with a prolonged selective IL-1 β-blockade. Even though the contribution of canakinumab in...
متن کاملCatheter-related Candidemia Caused by Candida haemulonii in a Patient in Long-term Hospital Care
Candida haemulonii, one of the non-albicans Candida species, is an emerging yeast pathogen that is known to be resistant to amphotericin B and other antifungal agents such as azoles. These anti-fungal agents have often been associated with clinical treatment failure, so no treatment regimen has been clearly established for invasive C. haemulonii infections. We investigated a catheter-related in...
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عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2012